CYB5R3 Mouse Monoclonal Antibody [Clone ID: LBI2A10]
Product Specifications
Background
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq]
Synonyms
B5R; DIA1
Gene Name
Cytochrome b5 reductase 3
Gene ID
1727
UniProt
P00387
Conjugation
Unconjugated
Related Pathways
Amino sugar and nucleotide sugar metabolism
Field of Research
Amino sugar and nucleotide sugar metabolism
Concentration
0.76 mg/ml
Dilution
WB 1:200~500, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CYB5R3
Overview
CYB5R3 mouse monoclonal antibody, clone LBI2A10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1727
Uniprot URL
https://www.uniprot.org/uniprot/P00387
Curated Selection
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