CD5 Mouse Monoclonal Antibody [Clone ID: LBI6F7]
Product Specifications
Background
CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1) . CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2) .
Synonyms
LEU1; T1
Gene Name
CD5 molecule
Gene ID
921
UniProt
P06127
Conjugation
Unconjugated
Related Pathways
Hematopoietic cell lineage
Field of Research
Hematopoietic cell lineage
Concentration
0.96 mg/ml
Dilution
WB 1:500~2000, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD5
Overview
Anti-CD5 mouse monoclonal antibody, clone LBI6F7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=921
Uniprot URL
https://www.uniprot.org/uniprot/P06127
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