ElF2 alpha (EIF2S1) Mouse Monoclonal Antibody [Clone ID: LBI3H4]
Product Specifications
Background
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) . [supplied by OMIM]
Synonyms
EIF-2; eIF-2-alpha; EIF-2A; EIF-2alpha; EIF2; EIF2A
Gene Name
Eukaryotic translation initiation factor 2 subunit alpha
Gene ID
1965
UniProt
P05198
Conjugation
Unconjugated
Concentration
0.69 mg/ml
Dilution
WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
EIF2S1
Overview
Anti-EIF2S1 mouse monoclonal antibody, clone LBI3H4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1965
Uniprot URL
https://www.uniprot.org/uniprot/P05198
Curated Selection
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