ElF2 alpha (EIF2S1) Mouse Monoclonal Antibody [Clone ID: LBI3H4]

Product Specifications

Background

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) . [supplied by OMIM]

Overview

Anti-EIF2S1 mouse monoclonal antibody, clone LBI3H4

Synonyms

EIF-2; eIF-2-alpha; EIF-2A; EIF-2alpha; EIF2; EIF2A

Gene Name

Eukaryotic translation initiation factor 2 subunit alpha

Gene ID

1965

UniProt

P05198

Conjugation

Unconjugated

Concentration

0.69 mg/ml

Dilution

WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.