USP5 Mouse Monoclonal Antibody [Clone ID: LBI1A8]

Product Specifications

Background

Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]

Overview

Anti-USP5 mouse monoclonal antibody, clone LBI1A8

Synonyms

ISOT

Gene Name

Ubiquitin specific peptidase 5

Gene ID

8078

UniProt

P45974

Conjugation

Unconjugated

Concentration

0.73 mg/ml

Dilution

WB 1:2000, IHC 1:50

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protease

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.