RANGAP1 Mouse Monoclonal Antibody [Clone ID: LBI1B4]
Product Specifications
Background
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq]
Overview
Anti-RANGAP1 mouse monoclonal antibody, clone LBI1B4
Synonyms
Fug1; RANGAP; SD
Gene Name
Ran GTPase activating protein 1
Gene ID
5905
UniProt
P46060
Conjugation
Unconjugated
Concentration
0.81 mg/ml
Dilution
WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RANGAP1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5905
Uniprot URL
https://www.uniprot.org/uniprot/P46060
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