BTK Mouse Monoclonal Antibody [Clone ID: LBI3E9]
Product Specifications
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Overview
Anti-BTK mouse monoclonal antibody, clone LBI3E9
Synonyms
AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Gene Name
Bruton tyrosine kinase
Gene ID
695
UniProt
Q06187
Conjugation
Unconjugated
Related Pathways
B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency
Field of Research
B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BTK
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=695
Uniprot URL
https://www.uniprot.org/uniprot/Q06187
Frequently Asked Questions
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