BTK Mouse Monoclonal Antibody [Clone ID: LBI6H9]

Product Specifications

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Overview

Anti-BTK mouse monoclonal antibody, clone LBI6H9

Synonyms

AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA

Gene Name

Bruton tyrosine kinase

Gene ID

695

UniProt

Q06187

Conjugation

Unconjugated

Related Pathways

B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency

Field of Research

B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.