4-tert-Octylphenol
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology[1][2][3][4].
Product Specifications
CAS Number
[140-66-9]
UNSPSC
12352005
Hazard Statement
H315, H318, H410
Target
Apoptosis; DNA/RNA Synthesis; Endogenous Metabolite
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-tert-octylphenol.html
Purity
99.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(C)(C)CC(C)(C)C)C=C1
Molecular Formula
C14H22O
Molecular Weight
206.33
Precautions
H315, H318, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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