MCL1 Mouse Monoclonal Antibody [Clone ID: LBI3A12]
Product Specifications
Background
The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Overview
Anti-MCL1 mouse monoclonal antibody, clone LBI3A12
Synonyms
Bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
Gene Name
MCL1 apoptosis regulator, BCL2 family member
Gene ID
4170
UniProt
Q07820
Conjugation
Unconjugated
Concentration
0.95 mg/ml
Dilution
WB 1:2000, IHC 1:50, IF 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MCL1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4170
Uniprot URL
https://www.uniprot.org/uniprot/Q07820
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