RALBP1 Mouse Monoclonal Antibody [Clone ID: LBI1E2]

Product Specifications

Background

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin

Overview

Anti-RALBP1 (RIP1) mouse monoclonal antibody, clone LBI1E2

Synonyms

RIP1; RLIP1; RLIP76

Gene Name

RalA binding protein 1

Gene ID

10928

UniProt

Q15311

Conjugation

Unconjugated

Related Pathways

Pancreatic cancer, Pathways in cancer

Field of Research

Pancreatic cancer, Pathways in cancer

Concentration

0.8 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100, IP: 4ug/mL

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.