RALBP1 Mouse Monoclonal Antibody [Clone ID: LBI11B2]
Product Specifications
Background
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin
Synonyms
RIP1; RLIP1; RLIP76
Gene Name
RalA binding protein 1
Gene ID
10928
UniProt
Q15311
Conjugation
Unconjugated
Related Pathways
Pancreatic cancer, Pathways in cancer
Field of Research
Pancreatic cancer, Pathways in cancer
Concentration
0.84 mg/ml
Dilution
WB 1:2000, IF 1:100, Flow 1:100, IP: 4ug/mL
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RALBP1
Overview
Anti-RALBP1 (RIP1) mouse monoclonal antibody, clone LBI11B2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10928
Uniprot URL
https://www.uniprot.org/uniprot/Q15311
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