XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2E8]
Product Specifications
Background
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Overview
Anti-XRCC1 mouse monoclonal antibody, clone LBI2E8
Synonyms
RCC
Gene Name
X-ray repair cross complementing 1
Gene ID
7515
UniProt
P18887
Conjugation
Unconjugated
Related Pathways
Base excision repair
Field of Research
Base excision repair
Concentration
1 mg/ml
Dilution
WB 1:2000, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
XRCC1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7515
Uniprot URL
https://www.uniprot.org/uniprot/P18887
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