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LOX Mouse Monoclonal Antibody [Clone ID: LBI6B7]

Product Specifications

Background

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

LOX mouse monoclonal antibody, clone LBI6B7

Synonyms

MGC105112

Gene Name

Lysyl oxidase

Gene ID

4015

UniProt

P28300

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Secreted Protein

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

LOX

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4015

Uniprot URL

https://www.uniprot.org/uniprot/P28300

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