Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: LBI4C5]
Product Specifications
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Synonyms
HKII; HXK2
Gene Name
Hexokinase 2
Gene ID
3099
UniProt
P52789
Conjugation
Unconjugated
Related Pathways
Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus
Field of Research
Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus
Concentration
1 mg/ml
Dilution
WB 1:1000, IF 1:100, Flow 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HK2
Overview
Anti-HK2 (Hexokinase II) mouse monoclonal antibody, clone LBI4C5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3099
Uniprot URL
https://www.uniprot.org/uniprot/P52789
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