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Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: LBI4C5]

Product Specifications

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Overview

Anti-HK2 (Hexokinase II) mouse monoclonal antibody, clone LBI4C5

Synonyms

HKII; HXK2

Gene Name

Hexokinase 2

Gene ID

3099

UniProt

P52789

Conjugation

Unconjugated

Related Pathways

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

Field of Research

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

Concentration

1 mg/ml

Dilution

WB 1:1000, IF 1:100, Flow 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

HK2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3099

Uniprot URL

https://www.uniprot.org/uniprot/P52789

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