Livin (BIRC7) Mouse Monoclonal Antibody [Clone ID: LBI1D12]
Product Specifications
Background
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Overview
Anti-BIRC7 (Livin) mouse monoclonal antibody, clone LBI1D12
Synonyms
KIAP; LIVIN; ML-IAP; MLIAP; RNF50
Gene Name
Baculoviral IAP repeat containing 7
Gene ID
79444
UniProt
Q96CA5
Conjugation
Unconjugated
Concentration
0.36 mg/ml
Dilution
WB 1:1000, IHC 1:50, Flow 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BIRC7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=79444
Uniprot URL
https://www.uniprot.org/uniprot/Q96CA5
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