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HSP70-1A (HSPA1A) Mouse Monoclonal Antibody [Clone ID: LBI2C12]

Product Specifications

Background

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Overview

Anti-HSPA1A (Hsp70) mouse monoclonal antibody, clone LBI2C12

Synonyms

HEL-S-103; HSP70-1; HSP70-1A; HSP70.1; HSP70I; HSP72; HSPA1

Gene Name

Heat shock protein family A (Hsp70) member 1A

Gene ID

3303

UniProt

P0DMV8

Conjugation

Unconjugated

Related Pathways

Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

Field of Research

Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

HSPA1A

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3303

Uniprot URL

https://www.uniprot.org/uniprot/P0DMV8

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