ERAB (HSD17B10) Mouse Monoclonal Antibody [Clone ID: LBI3B5]
Product Specifications
Background
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Synonyms
17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD
Gene Name
Hydroxysteroid 17-beta dehydrogenase 10
Gene ID
3028
UniProt
Q99714
Conjugation
Unconjugated
Related Pathways
Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation
Field of Research
Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation
Concentration
0.5 mg/ml
Dilution
WB 1:2000
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HSD17B10
Overview
Anti-HSD17B10 mouse monoclonal antibody, clone LBI3B5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3028
Uniprot URL
https://www.uniprot.org/uniprot/Q99714
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