ERAB (HSD17B10) Mouse Monoclonal Antibody [Clone ID: LBI3B5]

Product Specifications

Background

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Overview

Anti-HSD17B10 mouse monoclonal antibody, clone LBI3B5

Synonyms

17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD

Gene Name

Hydroxysteroid 17-beta dehydrogenase 10

Gene ID

3028

UniProt

Q99714

Conjugation

Unconjugated

Related Pathways

Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation

Field of Research

Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation

Concentration

0.5 mg/ml

Dilution

WB 1:2000

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.