FH Mouse Monoclonal Antibody [Clone ID: LBI9G4]

Product Specifications

Background

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]

Overview

FH mouse monoclonal antibody, clone LBI9G4

Synonyms

FMRD; HLRCC; LRCC; MCL; MCUL1

Gene Name

Fumarate hydratase

Gene ID

2271

UniProt

P07954

Conjugation

Unconjugated

Related Pathways

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

Field of Research

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

Concentration

1 mg/ml

Dilution

WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.