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BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: LBI6E3]

Product Specifications

Background

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq]

Synonyms

Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1

Gene Name

BUB1 mitotic checkpoint serine/threonine kinase B

Gene ID

701

UniProt

O60566

Conjugation

Unconjugated

Related Pathways

Cell cycle

Field of Research

Cell cycle

Concentration

1 mg/ml

Dilution

WB 1:500~2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

BUB1B

Overview

BuB1B (BubR1) mouse monoclonal antibody, clone LBI6E3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=701

Uniprot URL

https://www.uniprot.org/uniprot/O60566

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