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FKBP51 (FKBP5) Mouse Monoclonal Antibody [Clone ID: LBI3E9]

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Synonyms

AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Gene Name

FKBP prolyl isomerase 5

Gene ID

2289

UniProt

Q13451

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

FKBP5

Overview

Anti-FKBP5 (FKBP51) mouse monoclonal antibody, clone LBI3E9

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2289

Uniprot URL

https://www.uniprot.org/uniprot/Q13451

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