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SSX2 Mouse Monoclonal Antibody [Clone ID: LBI4D10]

Product Specifications

Background

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX

Gene Name

SSX family member 2

Gene ID

6757

UniProt

Q16385

Conjugation

Unconjugated

Concentration

0.67 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

SSX2

Overview

Anti-SSX2 mouse monoclonal antibody, clone LBI4D10

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=6757

Uniprot URL

https://www.uniprot.org/uniprot/Q16385

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