Cytochrome P450 Reductase (POR) Mouse Monoclonal Antibody [Clone ID: LBI5B3]
Product Specifications
Background
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]
Synonyms
CPR; CYPOR; P450R
Gene Name
Cytochrome p450 oxidoreductase
Gene ID
5447
UniProt
P16435
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:50, IF 1:50, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, P450, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
POR
Overview
POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone LBI5B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5447
Uniprot URL
https://www.uniprot.org/uniprot/P16435
Curated Selection
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