KDM4C Mouse Monoclonal Antibody [Clone ID: LBI5B9]

Product Specifications

Background

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Overview

Anti-KDM4C mouse monoclonal antibody, clone LBI5B9

Synonyms

GASC1; JHDM3C; JMJD2C; TDRD14C

Gene Name

Lysine demethylase 4C

Gene ID

23081

UniProt

Q9H3R0

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.