VMAT2 (SLC18A2) Mouse Monoclonal Antibody [Clone ID: LBI9E11]

Product Specifications

Background

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Overview

Anti-SLC18A2 (VMAT2) mouse monoclonal antibody, clone LBI9E11

Synonyms

SVAT; SVMT; VAT2; VMAT2

Gene Name

Solute carrier family 18 member A2

Gene ID

6571

UniProt

Q05940

Conjugation

Unconjugated

Related Pathways

Parkinson's disease

Field of Research

Parkinson's disease

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.