Superoxide Dismutase 1 (SOD1) Mouse Monoclonal Antibody [Clone ID: LBI8B10]
Product Specifications
Background
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
Synonyms
ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Gene Name
Superoxide dismutase 1
Gene ID
6647
UniProt
P00441
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases
Field of Research
Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases
Concentration
1 mg/ml
Dilution
WB 1:1000~2000, IHC 1:50, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SOD1
Overview
SOD1 (Superoxide Dismutase 1) mouse monoclonal antibody, clone LBI8B10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6647
Uniprot URL
https://www.uniprot.org/uniprot/P00441
Curated Selection
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