Superoxide Dismutase 1 (SOD1) Mouse Monoclonal Antibody [Clone ID: LBI8B10]

Product Specifications

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]

Overview

SOD1 (Superoxide Dismutase 1) mouse monoclonal antibody, clone LBI8B10

Synonyms

ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD

Gene Name

Superoxide dismutase 1

Gene ID

6647

UniProt

P00441

Conjugation

Unconjugated

Related Pathways

Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

Field of Research

Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

Concentration

1 mg/ml

Dilution

WB 1:1000~2000, IHC 1:50, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.