SSB Mouse Monoclonal Antibody [Clone ID: LBI3F11]
Product Specifications
Background
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III (see MIM 606007) -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]) .
Overview
Anti-SSB mouse monoclonal antibody, clone LBI3F11
Synonyms
La; La/SSB; LARP3
Gene Name
Small RNA binding exonuclease protection factor La
Gene ID
6741
UniProt
P05455
Conjugation
Unconjugated
Related Pathways
Systemic lupus erythematosus
Field of Research
Systemic lupus erythematosus
Concentration
1 mg/ml
Dilution
WB 1:1000~2000, IHC 1:150, IF 1:100, IP 2ug/500ul
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SSB
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6741
Uniprot URL
https://www.uniprot.org/uniprot/P05455
Curated Selection
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