Rad9 (RAD9A) Mouse Monoclonal Antibody [Clone ID: LBI7B11]

Product Specifications

Background

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

Overview

Anti-RAD9A (RAD9) mouse monoclonal antibody, clone LBI7B11

Synonyms

RAD9

Gene Name

RAD9 checkpoint clamp component A

Gene ID

5883

UniProt

Q99638

Conjugation

Unconjugated

Concentration

2 mg/ml

Dilution

WB 1:2000 IHC 1:50

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.