SSB Mouse Monoclonal Antibody [Clone ID: LBI2C8]
Product Specifications
Background
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III (see MIM 606007) -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]) .
Overview
Anti-SSB mouse monoclonal antibody, clone LBI2C8
Synonyms
La; La/SSB; LARP3
Gene Name
Small RNA binding exonuclease protection factor La
Gene ID
6741
UniProt
P05455
Conjugation
Unconjugated
Related Pathways
Systemic lupus erythematosus
Field of Research
Systemic lupus erythematosus
Concentration
0.8 mg/ml
Dilution
WB 1:1000~2000, IHC 1:150, IF 1:100, IP 2ug/500ul
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SSB
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6741
Uniprot URL
https://www.uniprot.org/uniprot/P05455
Curated Selection
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