Melanoma gp100 (PMEL) Mouse Monoclonal Antibody [Clone ID: LBI7E3]

Product Specifications

Background

Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Overview

SILV (Melanoma gp100) mouse monoclonal antibody, clone LBI7E3

Synonyms

D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV

Gene Name

Premelanosome protein

Gene ID

6490

UniProt

P40967

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

FLOW 1:100, IHC: 1:150

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Secreted Protein, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.