Melanoma gp100 (PMEL) Mouse Monoclonal Antibody [Clone ID: LBI8A4]
Product Specifications
Background
Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity
Synonyms
D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
Gene Name
Premelanosome protein
Gene ID
6490
UniProt
P40967
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:1000, IHC: 1:150
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PMEL
Overview
Anti-SILV (Melanoma gp100) mouse monoclonal antibody, clone LBI8A4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6490
Uniprot URL
https://www.uniprot.org/uniprot/P40967
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