Adenylate Kinase 1 (AK1) Mouse Monoclonal Antibody [Clone ID: LBI19G4]
Product Specifications
Background
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3) . AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
Synonyms
HTL-S-58j
Gene Name
Adenylate kinase 1
Gene ID
203
UniProt
P00568
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Purine metabolism
Field of Research
Metabolic pathways, Purine metabolism
Concentration
1 mg/ml
Dilution
WB 1:500~1000, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
AK1
Overview
AK1 (Adenylate Kinase 1) mouse monoclonal antibody, clone LBI19G4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=203
Uniprot URL
https://www.uniprot.org/uniprot/P00568
Curated Selection
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