Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: LBI4D12]

Product Specifications

Background

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Overview

CK8 (Keratin 8) mouse monoclonal antibody, clone LBI4D12

Synonyms

CARD2; CK-8; CK8; CYK8; K2C8; K8; KO

Gene Name

Keratin 8

Gene ID

3856

UniProt

P05787

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:500~1000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.