ID2 Mouse Monoclonal Antibody [Clone ID: LBI10C3]
Product Specifications
Background
The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.
Synonyms
BHLHb26; GIG8; ID2A; ID2H
Gene Name
Inhibitor of DNA binding 2
Gene ID
3398
UniProt
Q02363
Conjugation
Unconjugated
Related Pathways
TGF-beta signaling pathway
Field of Research
TGF-beta signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:50, IF 1:50
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
ES Cell Differentiation/IPS, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ID2
Overview
ID2 mouse monoclonal antibody, clone LBI10C3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3398
Uniprot URL
https://www.uniprot.org/uniprot/Q02363
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