ID2 Mouse Monoclonal Antibody [Clone ID: LBI10C3]

Product Specifications

Background

The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.

Overview

ID2 mouse monoclonal antibody, clone LBI10C3

Synonyms

BHLHb26; GIG8; ID2A; ID2H

Gene Name

Inhibitor of DNA binding 2

Gene ID

3398

UniProt

Q02363

Conjugation

Unconjugated

Related Pathways

TGF-beta signaling pathway

Field of Research

TGF-beta signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:50, IF 1:50

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

ES Cell Differentiation/IPS, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.