VEGFA Mouse Monoclonal Antibody [Clone ID: LBI4G3]
Product Specifications
Background
VEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Overview
VEGFA (VEGF) mouse monoclonal antibody, clone LBI4G3
Synonyms
MVCD1; VEGF; VPF
Gene Name
Vascular endothelial growth factor A
Gene ID
7422
UniProt
P15692
Conjugation
Unconjugated
Related Pathways
Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, VEGF signaling pathway
Field of Research
Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, VEGF signaling pathway
Concentration
0.46 mg/ml
Dilution
WB 1:2500~5000
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
VEGFA
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7422
Uniprot URL
https://www.uniprot.org/uniprot/P15692
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