PDX1 Mouse Monoclonal Antibody [Clone ID: LBI2A12]
Product Specifications
Background
Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4) .
Synonyms
GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Gene Name
Pancreatic and duodenal homeobox 1
Gene ID
3651
UniProt
P52945
Conjugation
Unconjugated
Related Pathways
Maturity onset diabetes of the young, Type II diabetes mellitus
Field of Research
Maturity onset diabetes of the young, Type II diabetes mellitus
Concentration
1 mg/ml
Dilution
WB 1:20000, IHC 1:50, IF 1:50~100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDX1
Overview
Pdx1 mouse monoclonal antibody, clone LBI2A12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3651
Uniprot URL
https://www.uniprot.org/uniprot/P52945
Curated Selection
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