Oct4 (POU5F1) Mouse Monoclonal Antibody [Clone ID: LBI9B7]

Product Specifications

Background

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21; q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Overview

OCT4 mouse monoclonal antibody, clone LBI9B7

Synonyms

Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4

Gene Name

POU class 5 homeobox 1

Gene ID

5460

UniProt

Q01860

Conjugation

Unconjugated

Concentration

0.25 mg/ml

Dilution

WB 1:5000, IHC 1:50, IF 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.