FGF2 Mouse Monoclonal Antibody [Clone ID: LBI2H11]
Product Specifications
Background
BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Synonyms
BFGF; FGF-2; FGFB; HBGF-2
Gene Name
Fibroblast growth factor 2
Gene ID
2247
UniProt
P09038
Conjugation
Unconjugated
Related Pathways
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
Field of Research
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
Concentration
1 mg/ml
Dilution
WB 1:5000~10000
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FGF2
Overview
BFGF (FGF2) mouse monoclonal antibody, clone LBI2H11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2247
Uniprot URL
https://www.uniprot.org/uniprot/P09038
Curated Selection
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