LGG-1/Atg8 antibodies [APR33669G]

Tissue Location: Expressed in PLML touch receptor neuron and in the ventral nerve cord (PubMed:17327275) . Expressed in AIY interneurons (PubMed:30880001) .

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LGG-1/Atg8 antibodies [APR33669G].

Preautophagosomal structure. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, autophagosome membrane. Lysosome lumen. Mitochondrion. Cytoplasm. Cytoplasmic vesicle, phagosome membrane. Cell membrane; Lipid-anchor. Cell projection, dendrite. Perikaryon. Note=In embryos, diffuse cytoplasmic localization with some areas displaying a more punctate distribution (PubMed:19377305, PubMed:19167332, PubMed:24374177, PubMed:28806108, PubMed:20550938) . Specifically, upon fertilization localizes to autophagosomes around the male pronucleus (PubMed:24374177) . During the first embryonic divisions and after the 25-cell stage, localizes to a large population of autophagosomes, with another smaller population of autophagosomes containing both lgg-1 and lgg-2 (PubMed:24374177) Localization to autophagosomes is dependent on atg-7 (PubMed:24374177) Co-localizes with sepa-1 in cytoplasmic aggregates (PubMed:19167332, PubMed:28806108) . Partially localizes to the phagosome membrane of engulfed apoptotic cells (PubMed:22451698)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

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Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.