APLP1 Antibody (C-Term) [APR33625G]

Product Specifications

Background

Tissue Location: Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APLP1 Antibody (C-Term) [APR33625G].

Synonyms

Amyloid-like protein 1, APLP, APLP-1, C30, APLP1

Gene Name

APLP1

Gene ID

333

UniProt

P51693

Chromosomal Location

Cell membrane; Single-pass type I membrane protein

Applications

WB, FC

Dilution

FC--1:25 WB--1:2000

Function

May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity) . Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Molecular Weight

72176

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.