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MKS1 Antibody (N-Term) [APR33617G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MKS1 Antibody (N-Term) [APR33617G].

Synonyms

Meckel syndrome type 1 protein, MKS1

Gene Name

MKS1

Gene ID

54903

UniProt

Q9NXB0

Chromosomal Location

Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.

Applications

WB, FC, IF

Dilution

IF--1:25 FC--1:25 WB--1:2000

Function

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Molecular Weight

64528

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=54903

Uniprot URL

https://www.uniprot.org/uniprot/Q9NXB0

Available Sizes

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