Phospho-MYPT1 (Thr852) Antibody [APR33508G]

Product Specifications

Background

Tissue Location: Expressed in striated muscles, specifically in type 2a fibers (at protein level) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MYPT1 (Thr852) Antibody [APR33508G].

Synonyms

Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit, PPP1R12A, MBS, MYPT1

Gene Name

HGNC:7618

Gene ID

4659

UniProt

O14974

Chromosomal Location

Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments

Applications

Dilution

WB--1:1000

Function

Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Molecular Weight

115281

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.