Phospho-MYPT1 (Thr852) Antibody [APR33508G]
Product Specifications
Background
Tissue Location: Expressed in striated muscles, specifically in type 2a fibers (at protein level) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MYPT1 (Thr852) Antibody [APR33508G].
Synonyms
Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit, PPP1R12A, MBS, MYPT1
Gene Name
HGNC:7618
Gene ID
4659
UniProt
O14974
Chromosomal Location
Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments
Applications
WB
Dilution
WB--1:1000
Function
Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
Molecular Weight
115281
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4659
Uniprot URL
https://www.uniprot.org/uniprot/O14974
Available Sizes
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