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MGAT4B Antibody (N-Term) [APR33433G]

Product Specifications

Background

Tissue Location: Widely expressed. Strongly overexpressed in pancreatic cancer.

Synonyms

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, 2.4.1.145, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, GnT-IVb, N-acetylglucosaminyltransferase IVb, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb, MGAT4B

Gene Name

MGAT4B

Gene ID

11282

UniProt

Q9UQ53

Chromosomal Location

Golgi apparatus membrane; Single- pass type II membrane protein

Applications

WB

Dilution

WB--1:2000

Function

Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.

Molecular Weight

63198

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MGAT4B Antibody (N-Term) [APR33433G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=11282

Uniprot URL

https://www.uniprot.org/uniprot/Q9UQ53

Available Sizes

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