MGAT4B Antibody (N-Term) [APR33433G]
Product Specifications
Background
Tissue Location: Widely expressed. Strongly overexpressed in pancreatic cancer.
Synonyms
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, 2.4.1.145, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, GnT-IVb, N-acetylglucosaminyltransferase IVb, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb, MGAT4B
Gene Name
MGAT4B
Gene ID
11282
UniProt
Q9UQ53
Chromosomal Location
Golgi apparatus membrane; Single- pass type II membrane protein
Applications
WB
Dilution
WB--1:2000
Function
Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
Molecular Weight
63198
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MGAT4B Antibody (N-Term) [APR33433G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=11282
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQ53
Available Sizes
Curated Selection
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