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BANP Antibody (N-Term) [APR33411G]

Product Specifications

Background

Tissue Location: Down-regulated in breast cancer cell lines.

Synonyms

Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP, BEND1, SMAR1

Gene Name

BANP

Gene ID

54971

UniProt

Q8N9N5

Chromosomal Location

Nucleus.

Applications

WB

Dilution

WB--1:2000

Function

Controls V (D) J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity) .

Molecular Weight

56494

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BANP Antibody (N-Term) [APR33411G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=54971

Uniprot URL

https://www.uniprot.org/uniprot/Q8N9N5

Available Sizes

Curated Selection

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