NAT8L Antibody (N-Term) [APR33396G]

Product Specifications

Background

Tissue Location: Expressed in brain..

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NAT8L Antibody (N-Term) [APR33396G].

Synonyms

N-acetylaspartate synthetase, NAA synthetase, 2.3.1.17, Camello-like protein 3, N-acetyltransferase 8-like protein, NAT8L, CML3

Gene Name

NAT8L

Gene ID

339983

UniProt

Q8N9F0

Chromosomal Location

Cytoplasm. Membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane; Single-pass membrane protein. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment

Applications

IHC-P-Leica, WB

Dilution

IHC-P-Leica--1:250 WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays a role in the regulation of lipogenesis by producing N- acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.

Molecular Weight

32837

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.