SH3GL2 Antibody (C-term) [APR33203G]
Product Specifications
Background
Tissue Location: Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SH3GL2 Antibody (C-term) [APR33203G].
Synonyms
Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A
Gene Name
SH3GL2
Gene ID
6456
UniProt
Q99962
Chromosomal Location
Cytoplasm {ECO:0000250|UniProtKB:O35179}. Membrane {ECO:0000250|UniProtKB:O35179}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35179}. Early endosome {ECO:0000250|UniProtKB:Q62420}. Cell junction, synapse, presynapse {ECO:0000250|UniProtKB:O35179}
Applications
WB
Dilution
WB--1:2000
Function
Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Molecular Weight
39962
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6456
Uniprot URL
https://www.uniprot.org/uniprot/Q99962
Available Sizes
Curated Selection
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