CASP4 Antibody (C-Term) [APR33189G]
Product Specifications
Background
Tissue Location: Widely expressed, including in keratinocytes and colonic and small intestinal epithelial cells (at protein level) . Not detected in brain.
Synonyms
Caspase-4, CASP-4, ICE (rel) -II, Protease ICH-2, Protease TX, Caspase-4 subunit 1, Caspase-4 subunit 2, CASP4, ICH2
Gene Name
CASP4 {ECO:0000303|PubMed:15123740, ECO:0000312|HGNC:HGNC:1505}
Gene ID
837
UniProt
P49662
Chromosomal Location
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion Inflammasome. Secreted Note=Predominantly localizes to the endoplasmic reticulum (ER) Association with the ER membrane requires TMEM214 (PubMed:15123740) Released in the extracellular milieu by keratinocytes following UVB irradiation (PubMed:22246630) .
Applications
WB
Dilution
WB--1:2000
Function
235165802487979125119034222466302617408526173988265083692596435277975102351658026375003321094122512175226375003259643523210941232109412251217522637500325964352265083691512374022246630236617062511903477439987797510779759228314590
Molecular Weight
43262
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP4 Antibody (C-Term) [APR33189G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=837
Uniprot URL
https://www.uniprot.org/uniprot/P49662
Available Sizes
Curated Selection
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