CASP4 Antibody (Center) [APR33180G]

Product Specifications

Background

Tissue Location: Widely expressed, including in keratinocytes and colonic and small intestinal epithelial cells (at protein level) . Not detected in brain.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP4 Antibody (Center) [APR33180G].

Synonyms

Caspase-4, CASP-4, ICE (rel) -II, Protease ICH-2, Protease TX, Caspase-4 subunit 1, Caspase-4 subunit 2, CASP4, ICH2

Gene Name

CASP4 {ECO:0000303|PubMed:15123740, ECO:0000312|HGNC:HGNC:1505}

Gene ID

837

UniProt

P49662

Chromosomal Location

Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion Inflammasome. Secreted Note=Predominantly localizes to the endoplasmic reticulum (ER) Association with the ER membrane requires TMEM214 (PubMed:15123740) Released in the extracellular milieu by keratinocytes following UVB irradiation (PubMed:22246630) .

Applications

Dilution

WB--1:2000

Function

235165802487979125119034222466302617408526173988265083692596435277975102351658026375003321094122512175226375003259643523210941232109412251217522637500325964352265083691512374022246630236617062511903477439987797510779759228314590

Molecular Weight

43262

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.