AKAP8 Antibody (Center) [APR33144G]

Product Specifications

Background

Tissue Location: Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells

Synonyms

A-kinase anchor protein 8, AKAP-8, A-kinase anchor protein 95 kDa, AKAP 95, AKAP8, AKAP95

Gene Name

AKAP8

Gene ID

10270

UniProt

O43823

Chromosomal Location

Nucleus. Nucleus matrix. Nucleus, nucleolus. Cytoplasm {ECO:0000250|UniProtKB:Q9DBR0}. Note=Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis However, mitotic chromatin localization has been questioned. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution Exhibits partial localization to the nucleolus in interphase, where it colocalizes with UBTF/UBF, suggesting localization to the fibrillary center and/or to the dense fibrillary component. Colocalizes with GJA1 at the nuclear membrane specifically during cell cycle G1/S phase

Applications

Dilution

WB--1:2000

Function

94733381060133210791967119643801464110716980585221307941274038123995757162275972688027426683827

Molecular Weight

76108

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AKAP8 Antibody (Center) [APR33144G].