(Mouse) Epcam Antibody (C-term) [APR32992G]
Product Specifications
Synonyms
Epithelial cell adhesion molecule, Ep-CAM, Epithelial glycoprotein 314, EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, Epcam, Tacstd1
Gene Name
Epcam
Gene ID
17075
UniProt
Q99JW5
Chromosomal Location
Lateral cell membrane {ECO:0000250|UniProtKB:P16422}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P16422}. Cell junction, tight junction {ECO:0000250|UniProtKB:P16422}. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction {ECO:0000250|UniProtKB:P16422}
Applications
WB, IHC-P, FC
Dilution
FC--1:25 IHC-P--1:100~500 WB--1:1000
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity) .
Molecular Weight
35019
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (Mouse) Epcam Antibody (C-term) [APR32992G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=17075
Uniprot URL
https://www.uniprot.org/uniprot/Q99JW5
Available Sizes
Curated Selection
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